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Case study· Apthea Labs

Taking a Class II medical wearable from prototype to ISO 13485 production

Structuring EVT, DVT and PVT for a regulated product, and building the documentation trail auditors expect.

Client
Medtech start-up (under NDA)
Industry
Medical devices
  • 3Build phases, all passed on schedule
  • 0Major non-conformities at audit
  • 6 moPrototype to pilot production

The challenge

A funded medtech start-up had a working wearable prototype and a regulatory submission date. They had no manufacturing partner, no design history file structure and no internal operations staff.

Our approach

We split the programme into three gated build phases:

Phase Quantity Focus
EVT 50 Design verification, DFM feedback
DVT 300 Reliability, biocompatibility, test validation
PVT 1,000 Process validation (IQ/OQ/PQ), line capability

At each gate, the go/no-go decision was based on agreed exit criteria. Yield, test coverage and open CAPA items were all tracked on one shared dashboard.

Choosing a partner that fits a regulated product

We only shortlisted EMS providers with an active ISO 13485 certification and a track record of FDA and MDR audits. We checked traceability down to reel and lot level during the site audits.

Test strategy

Every unit goes through a combined boundary-scan and functional test. The results are logged against the device serial number, so the device history record is generated automatically.

Outcome

The client moved from prototype to pilot production in six months, and passed their notified body audit with no major non-conformities.

  • #medical
  • #ISO 13485
  • #NPI
  • #test

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